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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM1L
All Species:
16.67
Human Site:
S548
Identified Species:
26.19
UniProt:
O00429
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00429
NP_005681.2
736
81877
S548
A
P
A
S
Q
E
P
S
P
A
A
S
A
E
A
Chimpanzee
Pan troglodytes
XP_520720
896
98575
S708
A
P
A
S
Q
E
P
S
P
A
A
S
A
E
A
Rhesus Macaque
Macaca mulatta
XP_001086126
725
80517
P537
R
D
K
S
S
K
V
P
S
A
L
A
P
A
S
Dog
Lupus familis
XP_864886
736
81869
S548
A
P
A
S
Q
E
P
S
P
A
A
S
A
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1M6
742
82640
P554
A
P
A
S
Q
E
P
P
P
A
A
S
A
E
A
Rat
Rattus norvegicus
O35303
755
83890
S561
A
P
A
S
Q
E
P
S
P
A
A
S
A
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001073190
696
77727
Q515
M
N
N
N
I
E
E
Q
R
R
N
R
L
A
R
Frog
Xenopus laevis
NP_001080183
698
77807
P525
N
R
I
S
R
D
L
P
P
P
A
A
S
R
D
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
N508
A
D
A
C
G
L
M
N
N
N
I
E
E
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
Y547
T
S
E
S
I
S
W
Y
K
D
E
D
E
K
E
Honey Bee
Apis mellifera
XP_394947
721
81070
T533
V
P
S
T
T
N
T
T
S
M
T
S
L
P
E
Nematode Worm
Caenorhab. elegans
P39055
830
93389
W551
L
M
S
D
S
L
S
W
Y
K
D
D
E
E
K
Sea Urchin
Strong. purpuratus
XP_802061
717
80361
R530
A
E
S
V
P
E
N
R
E
K
N
D
K
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
R559
S
G
S
Q
I
K
T
R
S
F
L
G
R
Q
A
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
S574
T
N
G
I
N
G
T
S
S
I
S
S
N
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
98.5
99.1
N.A.
97.8
96.4
N.A.
N.A.
89.8
87
86
N.A.
33.9
66.8
35.6
68.7
Protein Similarity:
100
79.9
98.5
99.5
N.A.
98.3
97.2
N.A.
N.A.
91.8
90.9
90.3
N.A.
52.2
79.7
53.9
82.2
P-Site Identity:
100
100
13.3
100
N.A.
93.3
100
N.A.
N.A.
6.6
20
13.3
N.A.
6.6
13.3
6.6
13.3
P-Site Similarity:
100
100
33.3
100
N.A.
93.3
100
N.A.
N.A.
13.3
46.6
26.6
N.A.
13.3
33.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
45.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
65.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
40
0
0
0
0
0
0
40
40
14
34
14
40
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
0
7
0
7
0
0
0
7
7
20
0
0
14
% D
% Glu:
0
7
7
0
0
47
7
0
7
0
7
7
20
40
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
7
7
0
7
7
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
7
20
0
0
0
0
7
7
0
0
7
0
% I
% Lys:
0
0
7
0
0
14
0
0
7
14
0
0
7
7
7
% K
% Leu:
7
0
0
0
0
14
7
0
0
0
14
0
14
0
0
% L
% Met:
7
7
0
0
0
0
7
0
0
7
0
0
0
0
0
% M
% Asn:
7
14
7
7
7
7
7
7
7
7
14
0
7
0
0
% N
% Pro:
0
40
0
0
7
0
34
20
40
7
0
0
7
7
7
% P
% Gln:
0
0
0
7
34
0
0
7
0
0
0
0
0
20
0
% Q
% Arg:
7
7
0
0
7
0
0
14
7
7
0
7
7
7
14
% R
% Ser:
7
7
27
54
14
7
7
34
27
0
7
47
7
0
7
% S
% Thr:
14
0
0
7
7
0
20
7
0
0
7
0
0
0
0
% T
% Val:
7
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _